It seems that March Madness applies not only to the weather, but also to the shenanigans at Seattle Grace Hospital, because now it appears that, despite having consumed an entire bottle of booze, Izzie and George DID have sex (more than once!) and now Izzie thinks their hook-up was "God's plan" or something, because it was so very, very right, even though those of us who've been playing along at home have never seen any evidence of sexual chemistry between the two of them ever. After a lot of hangover-induced, guilt-ridden agony from George and squirrelly behavior from Izzie and a very poorly timed visit from Callie's dad, Hector Elizondo, George tells Izzie that he can't tell Callie about their assignation, because it wouldn't be fair to hurt Callie just to ease his conscience. Izzie reluctantly agrees, but does a lot of crying, because…she's in love with George? If you say so.

As far as everyone else goes, Cristina overly relates to a man who has to have his foot amputated, which somehow leads to her patching it up with Burke, agreeing to have a wedding. Because he's her metaphorical other foot or something. (I generally enjoy the way this show uses symbolism, but come on.) Meredith's hair looks awesome, and she successfully performs a fancy-schmancy bone-grafting procedure under the guidance of McSteamy, despite some overprotective yada yada from McDreamy, who seems to be having some kind of PTSD in the wake of Meredith's near-death experience. (And they say this show isn't getting soapy.) Meredith's pretty sure her dead mother would be proud of her for this, which is a nice step toward avoiding getting into the kind of emotional state where you let yourself drown. Alex continues to be awesome in general, this week helping Crush choose her new face and admitting to her in the process that his nascent relationship with Addison is "complicated." And everyone else is acting totally batty because they're being interviewed for the Chief position and suspect to a man that Marlowe is going to sweep it out from under them.